There was a paper that suggested vaccinated individuals carry a 251x higher viral load (with delta variant) in their nose. That seems like an absurd number; too high to pass the sniff test (no pun intended), but could there be some truth to vaccinated individuals being more infectious to the unvaccinated?
There was a paper that suggested vaccinated individuals carry a 251x higher viral load (with delta variant) in their nose. That seems like an absurd number; too high to pass the sniff test (no pun intended), but could there be some truth to vaccinated individuals being more infectious to the unvaccinated?
And same for partially vaccinated infecting other partially vaccinated more or better than any other group.
This suggests the real susceptibility is homologous immune status rather than heterologous immune status. In simpler terms- people in similar immunological situation or developmental stage in their pandemic evolution likely are easy targets for the virus to target because they have fewer differences between their immune responses to overcome in order to infect.
It was a comparison of unvaccinated healthcare workers infected with original Wuhan strain in early 2020 vs Delta variant in June when healthcare workers were fully vaccinated with AZ. The comparison was not with contemporaneous delta variant in unvaccinated in Vietnam.
However, there was a dataset that did show the viral cultures are more infectious on average at the same CT value from Wisconsin which was mysteriously deleted from the website two days after I posted it in Vejon Health's Malone Vanden Bossche panel discussion on Viral load.
My graphic showing higher infectious growth at same viral load from original dataset: https://ibb.co/cygjCpH
There was a paper that suggested vaccinated individuals carry a 251x higher viral load (with delta variant) in their nose. That seems like an absurd number; too high to pass the sniff test (no pun intended), but could there be some truth to vaccinated individuals being more infectious to the unvaccinated?
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3897733
Keeping all things constant, they found vaccinated got infected with delta at 250% the rate as Unvaccinated.
https://www.nejm.org/doi/suppl/10.1056/NEJMoa2108891/suppl_file/nejmoa2108891_appendix.pdf
Dutch household secondary attack rate study found 1.16x enhanced transmission between fully vaccinated index and contact.
https://doi.org/10.1101/2021.10.14.21264959
And same for partially vaccinated infecting other partially vaccinated more or better than any other group.
This suggests the real susceptibility is homologous immune status rather than heterologous immune status. In simpler terms- people in similar immunological situation or developmental stage in their pandemic evolution likely are easy targets for the virus to target because they have fewer differences between their immune responses to overcome in order to infect.
It was a comparison of unvaccinated healthcare workers infected with original Wuhan strain in early 2020 vs Delta variant in June when healthcare workers were fully vaccinated with AZ. The comparison was not with contemporaneous delta variant in unvaccinated in Vietnam.
However, there was a dataset that did show the viral cultures are more infectious on average at the same CT value from Wisconsin which was mysteriously deleted from the website two days after I posted it in Vejon Health's Malone Vanden Bossche panel discussion on Viral load.
My graphic showing higher infectious growth at same viral load from original dataset: https://ibb.co/cygjCpH
Altered and manipulated dataset from still online after September 30 study https://go.wisc.edu/p22l16